Research
PubMed Publications
OCT-Angiography
Biomarkers in Ophthalmic Imaging
Artificial Intelligence
Find Us on PubMed
The lab’s PubMed publications can be found in our NCBI collection.
OCT-Angiography
First introduced in 1991, Optical Coherence Tomography (OCT) marks one of the biggest advances in ophthalmic imaging, which came out of a collaboration between MIT, Mass Eye and Ear, and MGH. As OCT technology advances, we aim to utilize our state-of-the-art devices, namely Swept-Source OCT-Angiography, to evaluate their utility in diagnosis and prognosis of ocular and systemic diseases, such as diabetic retinopathy and age-related macular degeneration.
Biomarkers in Ophthalmic Imaging
Early detection is often critical to treatment of diseases. Our current studies aim to identify novel and robust biomarkers, such as thinning of the vasculature, widening of the foveal avascular zone, and density within the multiple vascular layers, for patients with various retinal and choroidal disorders such as diabetic retinopathy and age-related macular degeneration and well as systemic diseases, such as Alzheimer’s disease, schizophrenia, and COVID-19 infection.
Artificial Intelligence
Artificial intelligence (AI) is changing healthcare and has many potential applications in the field of retina. With collaborations within the MGB system, our lab aims to investigate the utility of machine learning in the context of retinal imaging research.
Quick Contrast Sensitivity Function (qCSF) Testing
Growing evidence supports the use of alternative tests for visual function, such as contrast sensitivity, which may better reflect subtle changes in visual function and vision-related quality of life compared to VA. The quantitative contrast sensitivity function (qCSF) method uses active learning algorithms to evaluate contrast sensitivity across multiple different spatial frequencies. It can be used to assist in detection of various retinal diseases.