First introduced in 1991, Optical Coherence Tomography (OCT) marks one of the biggest advances in ophthalmic imaging, which came out of a collaboration between MIT, Mass Eye and Ear, and MGH. As OCT technology advances, we aim to utilize our state-of-the-art devices, namely Swept-Source OCT-Angiography, to evaluate their utility in diagnosis and prognosis of ocular and systemic diseases, such as diabetic retinopathy and age-related macular degeneration.